在MSM与mopox的HPV联合感染的流行病学和类型特征:基于医院的前性研究
Tianyang Liu1, Siwei Zhang1, Liuqing Yang2
1Institute for Hepatology, Shenzhen Third People's Hospital; The Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen, Guangdong, China.
Journal of infection and public health
|November 19, 2024
概括
蒙波克斯患者经常同时感染人类乳头瘤病毒 (HPV),通常是多种高风险类型. 加强HPV查和预防对于感染mopox的人来说至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 病毒学 病毒学
- 公共卫生 公共卫生
背景情况:
- 马博克斯疫情显示出多样化的传播,性接触对IIb菌株具有重要意义.
- 人类乳头瘤病毒 (HPV) 是一种常见的性传播感染.
- 关于mpox患者的HPV共感染和基因型分布的研究有限.
研究的目的:
- 为了调查HPV的流行率和基因型分布,与男性发生性关系的男性 (MSM) 诊断出pomox.
- 在这个人群中探索HPV感染,HIV状况和mopox之间的关联.
主要方法:
- 一项研究于2023年5月至9月在深第三人民医院进行.
- 从mpox患者收集了社会人口统计和临床数据.
- 分析了用于HPV基因定型的头拭子.
主要成果:
- 在73例MSMmpox病例中,80.4%的HPV检测呈阳性.
- 多重HPV感染很常见 (56.9%),特别是在HIV阳性个体中 (93%).
- HPV16是最常见的高风险基因型;HPV感染与HIV显著相关 (p=0.001).
结论:
- 在mpox患者中观察到HPV的高患病率,包括多种高风险类型.
- HPV感染与艾滋病毒共感染和mopox检测部位有显著的关联.
- 强化HPV查,预防和治疗是建议个人与mopox.
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