遗传和代谢因素影响黄色羽毛 brojlers 的皮肤黄色
Rongqin Huang1, Xianqi Deng1, Jingwen Wu1
1Department of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture and Rural Affair, South China Agricultural University, Guangzhou 510642, China.
氨酸是导致黄羽毛肉皮肤变黄的主要颜料. 血清中黄蛋白度可以预测皮肤颜色,有助于为所需的肉特征提供育种计划.
科学领域:
- 动物科学动物科学
- 遗传学 遗传学 是一个
- 生物化学 生物化学
背景情况:
- 皮肤的黄色显著影响了黄色羽毛 brojlers 的市场价值.
- brojiler 皮肤颜色的特定颜料和遗传基础在很大程度上仍然没有特征.
研究的目的:
- 为了确定导致肉皮肤黄色的主要颜料.
- 建立一个用于预测皮肤黄色的分子标记.
- 阐明调节胡卜素代谢和在肉皮肤中的沉积的遗传因素.
主要方法:
- 光谱光度分析以量化皮肤的黄色.
- 高性能液体色谱 (HPLC) 用于识别皮肤颜料.
- RNA测序 (RNA-Seq) 用于分析不同皮肤黄色的肉中的基因表达.
- 基因定型用于识别与皮肤颜色相关的遗传变异.
主要成果:
- 氨酸被确定为主要的胡卜素,负责皮肤黄色.
- 血清黄蛋白度与皮肤黄色有很强的相关性,作为预测标志物.
- RNA-Seq分析揭示了几种候选基因 (例如,CYP26A1,CYP1B1,CYP2C18,CYP2W1,HSD17B2,AOX1,KMO,PLIN1,RET) 可能参与胡卜素代谢和沉积.
- 在CYP1A1基因中的单核酸多态 (SNP) 与马黄的皮肤黄色之间发现了显著的关联.
结论:
- 氨酸是决定黄羽毛肉皮肤颜色的关键色素.
- 血清黄蛋白度是一种可行的分子标记物,用于评估和预测皮肤黄色.
- 已识别的基因和SNP为皮肤颜色的遗传调节提供了关键的见解,为肉养殖计划中的标记器辅助选择提供了有价值的目标.
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