相关实验视频

Updated: Jun 7, 2025

Author Spotlight: Unveiling the Role of SNF2L in Replication Fork Stability and Genome Duplication
05:55

Author Spotlight: Unveiling the Role of SNF2L in Replication Fork Stability and Genome Duplication

Published on: August 23, 2024

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领先和滞后链模板中的DNA切断可以触发破裂诱导的复制

Yuanlin Xu1, Carl A Morrow1, Yassine Laksir1

  • 1Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

Molecular cell
|November 19, 2024
PubMed
概括

复制压力会导致DNA断裂,有时导致断裂诱导的复制 (BIR),这是一个变种过程. 这项研究表明,领先和落后的链断裂都可能触发BIR,特别是当分叉收延迟或Ku70缺席时.

关键词:
这就是CRISPR-Cas9n.复制DNA复制DNA复制DNA复制弗莱克尼克 (Flp-nick) 是一个很棒的人.破裂诱导的复制.双链断裂断裂的方法同类的重组组合.复制子复制子复制分叉的崩复制分叉的崩复制重新启动复制.单链断裂断裂是一种单链断裂.

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