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Updated: Jun 7, 2025

Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles
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Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles

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一个三位一体的STING激活纳米粒子利用癌细胞的STING机械来增强免疫疗法

Yanming Xia1, Bo Shi1, Keke Wang2

  • 1Department of Pharmaceutics, Jiang Su Key Laboratory of Drug Design and Optimization, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.

Journal of controlled release : official journal of the Controlled Release Society
|November 19, 2024
PubMed
概括

这项研究引入了一种新型纳米粒子 (CMTP),可以激活癌细胞内的cGAS-STING通路,而不是宿主细胞. 这种方法有效地提高了抗瘤免疫力,即使在挑战感冒瘤时也是如此.

关键词:
癌症免疫疗法癌症免疫疗法协调纳米粒子的纳米粒子.线粒体DNA是线粒体的DNA.cGAS-STING 的使用情况.

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