相关实验视频
Updated: Jun 7, 2025
08:49
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
15.7K
新斯科舍省皮肤黑色素瘤的趋势,重点关注2007年至2019年
Rachel A Dorey1, Gordon Walsh2, Ron Dewar2
1Faculty of Medicine, Dalhousie University, Halifax, NS, Canada.
Journal of cutaneous medicine and surgery
|November 19, 2024
概括
在新斯科舍省,黑色素瘤的发病率正在上升,特别是在现场病例中. 通过公众和医生教育对有色素的皮肤病变的早期检测和持续的阳光安全宣传至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 公共卫生 公共卫生
- 癌症流行病学 癌症流行病学
背景情况:
- 黑色素瘤在加拿大构成了严重的公共卫生威胁,每年有超过1000人死亡.
- 新斯科舍省和爱德华王子岛历来报告了加拿大黑色素瘤发病率最高的地区.
研究的目的:
- 分析1992年至2021年新斯科舍省黑色素瘤发病率和死亡率的趋势.
- 检查2007年至2019年间诊断的黑色素瘤病例的人口统计和特定地点数据.
主要方法:
- 利用来自新斯科舍省癌症登记处的数据来诊断黑色素瘤和死亡.
- 雇员联结点趋势分析软件用于评估发病率 (1992-2019) 和死亡率 (1992-2021).
- 包括从2007年到2017年诊断的病例的TNM分期数据.
主要成果:
- 在2007年至2019年期间,记录了2450例现场和4063例侵入性黑色素瘤病例;52.8%是男性.
- 自1992年以来,侵袭性黑色素瘤的发病率每年增加2.7%,而现场黑色素瘤的发病率每年增加4.9%.
- 五年净生存率仍在92%左右,晚期黑色素瘤生存率略有改善.
结论:
- 新斯科舍省黑色素瘤发病率不断上升,需要加强公众和医生对识别有色素的皮肤病变的教育.
- 早期发现非典型的黑色素细胞病变对于改善患者的治疗结果至关重要.
- 建议继续强调新斯科舍省的阳光安全实践.
相关概念视频
01:30Skin Cancer
3.7K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
3.7K
01:14Changes in Skin Color: Clinical Perspectives
1.7K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
1.7K
01:21Cancer Survival Analysis
328
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
328
02:07Tumor Progression
6.2K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.2K