在围产期中风后,右侧大脑皮层中的句子处理和情感表达的功能分区在围产期中风后
Kelly C Martin1, Anna Seydell-Greenwald2,3, Peter E Turkeltaub2,3
1Center for Brain Plasticity and Recovery, Georgetown University Medical Center, Georgetown University, Washington, DC, 20057, USA. kcm81@georgetown.edu.
在早期左半球中风之后,右半球支持语言. 脑部成像显示,在中风幸存者中,句子和情感表情处理的重叠程度低于预期,这表明空间隔离是关键.
科学领域:
- 神经科学是一个神经科学.
- 发育神经科学的发展神经科学.
- 认知神经科学是一种认知神经科学.
背景情况:
- 通常,左半球 (LH) 支持句子处理,而右半球 (RH) 支持健康成年人的情感表达.
- 早期的LH中风可能会导致RH对这两种功能进行补偿,这引发了关于RH功能组织的问题.
研究的目的:
- 调查早期LH中风的个体的RH中如何组织句子处理和情感表达.
- 要确定这些功能在LH中风后的RH中是否比预期的多或少重叠.
主要方法:
- 使用基于任务的功能磁共振成像 (fMRI).
- 参与者包括患有影响LH (LHPS) 周围动脉缺血性中风的个人及其健康的兄弟姐妹.
- fMRI任务探测了听觉句子处理和情感prosody处理.
主要成果:
- 患有LH围产性中风的个体在RH激活中对于句子处理和情感表达的重叠比通过简单的镜像预测的要少.
- 这表明,功能空间分离在RH中保持或重新建立.
结论:
- 在早期LH中风后,RH对语言的功能组织可能会保持不同语言能力之间的空间隔离.
- 这种分离可能对高效的语言处理至关重要,当LH在发育早期受到损害时.
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