艾滋病毒和HCV共感染者住院和死亡人数
Dorota Zarębska-Michaluk1, Piotr Rzymski2, Krzysztof Kanecki3
1Department of Infectious Diseases and Allergology, Jan Kochanowski University, Kielce, Poland.
Scientific reports
|November 20, 2024
概括
波兰人类免疫缺陷病毒 (HIV) 和型肝炎病毒 (HCV) 联合感染的住院率在COVID-19大流行期间下降. 男性的病例死亡率增加,但女性的病例死亡率没有增加,由于难民涌入而没有出现升级.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 与艾滋病毒和HCV的同时感染是一个重大的全球健康挑战.
- 了解共感染住院的趋势对于公共卫生规划至关重要.
研究的目的:
- 分析2012-2022年波兰艾滋病毒/HCV共感染的住院趋势和结果.
- 评估COVID-19大流行和难民涌入对这些趋势的影响.
主要方法:
- 追溯性,基于人群的研究设计.
- 对住院率,人口统计,临床特征和病例死亡率的分析.
- 包括跨越大流行前,大流行和难民涌入时期的数据.
主要成果:
- 平均每年住院率为1.33每10^5,与大流行前 (1.63每10^5) 相比,在大流行期间 (0.51每10^5) 显著下降.
- 在疫情期间,住院病例死亡率在男性中上升 (1.83至3.93),但在女性中保持稳定 (1.53).
- 尽管乌克兰难民涌入,但2022年没有观察到住院病例的显著增加.
结论:
- 随着COVID-19大流行,艾滋病毒/HCV共感染住院病例减少,男性死亡率显著上升.
- 在研究期间,战争难民的涌入并没有使波兰艾滋病毒/HCV共感染的流行病学情况升级.
- 持续监测波兰艾滋病毒/HCV共感染人口是必不可少的.
相关概念视频
Retrovirus Life Cycles
45.7K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
45.7K
Sexually Transmitted Infections
279
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
279
Pulmonary Tuberculosis I
220
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
220
Diseases of the Liver and Gallbladder
475
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
475
Healthcare Associated Infections II: Preventive Measures
2.5K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.5K
Immunodeficiency Diseases
909
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
909


