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Updated: Jun 7, 2025

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation
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Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

Published on: September 20, 2017

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ZBTB48是一种调节B细胞特异性CIITA表达的原始化因子

Grishma Rane1, Vivian L S Kuan1, Suman Wang2

  • 1Cancer Science Institute of Singapore, National University of Singapore, 117599, Singapore, Singapore.

The EMBO journal
|November 20, 2024
PubMed
概括

该研究确定ZBTB48是B细胞中MHCII类 (CIITA) 表达的关键调节者. ZBTB48充当开关,控制CIITA基因激活,这对适应性免疫至关重要.

关键词:
B 细胞 B 细胞城市 城市 城市表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.基因表达 基因表达在MHC II中,MHC II是最重要的.

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