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Updated: Jun 7, 2025

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
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Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients

Published on: October 15, 2017

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在食品和药物管理局不良事件报告系统数据库中对famciclovir的药监测研究

Runan Fang1,2, Yang Zhou2,3, Lu Han1,2

  • 1Dongzhimen Hospital Beijing University of Chinese Medicine, No.5 Haiyun Cang, Dongcheng District, Dermatology, Beijing, Beijing, 100700, China.

Scientific reports
|November 20, 2024
PubMed
概括

这项研究使用FAERS数据库分析了famciclovir不良事件 (AE). 它确定了恶心和头痛等常见的副作用,以及目前药物标签中未列出的潜在的新安全信号.

关键词:
不良事件是不良事件.公平的人是公平的.这种药物是Famciclovir.药物监督 药物监督 药物监督

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Published on: July 15, 2019

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Author Spotlight: Addressing Regulatory Gaps in Molecular Studies by Quantifying Viral Vectors in Complex Matrices07:43

Author Spotlight: Addressing Regulatory Gaps in Molecular Studies by Quantifying Viral Vectors in Complex Matrices

Published on: July 14, 2023

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Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
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Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
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Antiepileptic drugs, such as levetiracetam (Keppra) and brivaracetam (Briviact), have emerged as crucial tools in managing epilepsy. These medications exert their therapeutic effects by targeting the synaptic vesicle protein SV2A, a transmembrane glycoprotein primarily found in the brain.
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