稳定性胸痛:病理生理学,诊断及其管理的综述
Anurag Sharma1, Tushor Roy2, Paramartha Bhattacharya3
1Chairperson, Department of Cardiology, Ojas Super Specialty Hospital, Panchkula, Haryana, India.
The Journal of the Association of Physicians of India
|November 20, 2024
概括
印度面临着日益严重的心血管疾病 (CVD) 流行,冠状动脉疾病 (CAD) 每年造成数百万人的死亡. 本综述侧重于通道阻断剂 (CCBs) 用于治疗胸痛,这是CAD的一个关键症状.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 印度正在经历心血管疾病 (CVD) 的激增,由城市化和生活方式的变化驱动.
- 冠状动脉疾病 (CAD) 和缺血性心脏病 (IHD) 表现为胸痛,导致印度每年超过700万人死亡.
- 低收入和中等收入国家面临的挑战包括缺乏意识,缺乏医疗保健,缺乏对CAD管理的负担能力.
研究的目的:
- 审查对心肌痛的抗性治疗选择.
- 讨论通道阻塞剂 (CCBs) 的作用,特别是二皮素 (DHPs) 和非二皮素,在治疗胸痛时的作用.
- 突出在CAD预防和管理方面需要共同努力的需要.
主要方法:
- 关于抗血管性药物的文献综述.
- 抗性药物的分类为一线 (CCB,β阻塞剂,短效酸盐) 和二线 (伊瓦布拉丁,尼科兰迪尔,拉诺拉,trimetazidine) 的治疗方法.
- 专注于用于心痛管理的不同类型的CCB.
主要成果:
- CCBs是第一线抗风脉治疗的关键组成部分.
- 双胺酸 (DHP) 和非双胺酸代表了具有不同机制的不同类型的CCB.
- 有效的管理需要改变生活方式,药物治疗和预防策略的结合.
结论:
- 通道阻断剂在胸痛的药理管理中至关重要.
- 了解DHP和非DHPCCB之间的细微差别对于优化治疗至关重要.
- 综合患者与医生的合作对于解决印度日益加剧的心血管疾病负担至关重要.
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