在急性精神病学住院病房进行心理治疗试验的核心结果集的开发
Pamela Jacobsen1, Katherine Berry2,3, Lucy Clarkson4
1Department of Psychology, University of Bath, Bath, BA2 7AY, UK. pcj25@bath.ac.uk.
BMC psychiatry
|November 20, 2024
概括
针对急性精神病住院患者的心理治疗试验,开发了6个关键结果的核心结果集 (COS). 这一标准化套件确保了有意义和可比的结果,提高了研究效率和临床实践实施.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 在急性精神病医院住院患者试验中,心理治疗的结果措施缺乏共识.
- 为了有意义的试验结果,包括多样化的观点,特别是服务用户的重要性.
- 需要一个核心结果集 (COS) 来标准化结果测量和改进数据合成.
研究的目的:
- 开发一种基于共识的核心成果集 (COS),用于在急性精神病室住院患者中进行心理治疗试验.
- 确保试验结果具有意义,重要,并反映利益相关者的优先事项.
主要方法:
- 使用了三个阶段的过程:系统审查,在线利益相关者调查和定性访谈,以编制长长的结果列表.
- 一项涉及50个利益相关者的e-Delphi调查将长清单精细化为12个结果的短清单.
- 与9个利益相关者的最终共识会议确定了最终的6个结果COS.
主要成果:
- 从系统性审查,调查和采访中生成了一个长长的68个结局列表.
- 通过e-Delphi流程将结果减少到12个,而共识会议将结果最终确定为6个.
- 推的COS包括:应对能力,希望,生活质量,精神病症状,情绪和自我伤害行为.
结论:
- 广泛采用6个结果COS将减少研究浪费,并提高临床试验数据的可比性.
- COS确保了利益相关者的优先事项的代表性,促进了有效疗法的识别和实施.
- 拟议的COS可用于住院试验,未来的工作重点是最佳测量仪器,包括患者报告的结果.
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