治疗高胆固醇血症的食补充剂的有效性,副作用,坚持性,可负担性和采购:叙述性审查
Isabel von Känel-Cordoba1, Katharina Wirnitzer2,3,4,5, Katja Weiss1
1Institute of Primary Care, University of Zurich, Zurich, Switzerland.
Journal of health, population, and nutrition
|November 20, 2024
概括
饮食补充剂,如红酵母大米,亚麻和柏格莫特,显示在降低胆固醇方面具有前途. 需要进一步的研究来证实这些天然高胆固醇血治疗方法的有效性和解决质量控制问题.
科学领域:
- 心血管健康 心血管健康
- 营养保健品 营养保健品
- 药理学 药理学是指药理学的学科.
背景情况:
- 类药物有效降低高胆固醇,但可能引起副作用,促使患者对替代品感兴趣.
- 食补充剂 (DS) 正被探索为高胆固醇血症的潜在治疗方法.
- 本综述评估了胆固醇管理的DS,考虑了有效性,安全性,坚持性,成本和可访问性.
研究的目的:
- 评估各种食补充剂的疗效和安全性,以控制高胆固醇血症.
- 为了比较特定补充剂与传统的他类药物治疗的有效性.
- 为了识别具有降胆固醇特性的关键天然成分.
主要方法:
- 对2012年至2024年间发表的研究进行叙述性审查.
- 搜索了PubMed,Scopus和Cochrane数据库的"高胆固醇血症"与特定的食补充剂 (红酵母大米,亚麻,桃,大,柏格莫特) 结合.
- 包括没有语言限制的研究,直到2024年1月28日.
主要成果:
- 食补充剂,包括亚麻种,柏格莫特和红酵母大米,显示出降低胆固醇水平的潜力.
- 降低胆固醇的程度在研究和补充剂之间有所不同.
- 红酵母大米,桃提取物,柏格莫特,大和亚麻等天然成分具有降胆固醇的特性.
结论:
- 红酵母大米,柏格莫特和亚麻对高胆固醇治疗有很大的前景,但疗效各不相同.
- 建议进行全面的队列研究,以验证这些DS的有效性.
- 对DS的质量控制和缺乏监督的担忧需要进一步调查,以及对它们的分子机制的研究.
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