[BCG治疗非肌肉侵入性膀癌:当前趋势的概述]
M Dymov A1,2,3,4, A Lee Yu1,2,3,4, P Korchagin M1,2,3,4
1Institute for Urology and Human Reproductive Health of FGAOU I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Urologiia (Moscow, Russia : 1999)
|November 20, 2024
概括
由于设施不足或药物短缺,三分之一的俄罗斯泌尿科医生避免在非肌肉侵入性膀癌 (NMIBC) 中使用静脉BCG治疗. 改善条件可以提高NMIBC患者的无复发生存率.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
背景情况:
- 非肌肉侵入性膀癌 (NMIBC) 的复发率高 (70%) 和进展风险高 (20%).
- 肠道 Calmette-Guérin (BCG) 疗法对于增加中期和高风险NMIBC中无复发的生存率至关重要.
- 这项研究研究了目前在俄罗斯的静脉内BCG治疗的应用.
研究的目的:
- 评估在俄罗斯泌尿病学会的泌尿科医生中使用静脉BCG疗法.
- 确定阻碍BCG疗法在NMIBC治疗中的广泛采用障碍.
主要方法:
- 在145名俄罗斯泌尿科医生中进行了一项调查.
- 该调查收集了关于BCG疗法处方实践,非处方原因和经历困难的数据.
主要成果:
- 在接受调查的泌尿科医生中,有32%的人没有为NMIBC开布BCG治疗.
- 主要障碍包括缺乏足够的设施 (74%) 和药物不可用 (20%).
- 免疫疫苗 (69%) 是最常被处方的BCG药物,只有8%的医生报告没有治疗困难.
结论:
- 相当一部分泌尿科医生面临的挑战是在注射静脉BCG治疗.
- 解决设施限制和药物供应问题对于优化BCG免疫疗法对NMIBC患者至关重要.
- 改善静脉内免疫疗法的条件可以提高NMIBC的无复发生存率.
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