在印度卡纳塔克邦的第三级护理医院参观的尿路感染患者中,Enterococcus物种的抗生素图案
Sujatha Bhat1, Dushan Uvindu Gunawardana2, Delisha Kaur Boparai2
1Division of Microbiology, Department of Basic Medical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Antimicrobial stewardship & healthcare epidemiology : ASHE
|November 20, 2024
概括
肠球菌导致与医疗相关的感染,抗生素耐药性正在上升. 这项研究在尿路感染中发现了多药耐药的Enterococcus faecalis菌株,需要仔细选择抗菌疗法.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 肠球菌是医疗保健相关感染的日益严重的原因.
- 肠球菌中的抗菌素耐药性复杂化了尿路感染 (UTI) 的治疗.
研究的目的:
- 为了确定尿路感染中Enterococcus物种的流行率.
- 为了确定这些隔离物中的抗菌素耐药性模式.
- 在印度卡纳塔克邦的一家三级医院为肠球性尿道感染提供治疗策略的信息.
主要方法:
- 从2021年开始对4341个培养阳性尿样进行分析.
- 使用矩阵辅助激光吸附离子化-飞行质谱的飞行时间的细菌鉴定.
- 通过自动化的VITEK-2® COMPACT系统进行抗生素敏感性测试.
主要成果:
- 从159个 (3.66%) 样本中分离出肠球菌种.
- 菌 (64.7%) 和菌 (28.3%) 是主要的物种.
- 所有的分离物都对线佐利德,提科普拉宁和万科米敏感.
- 观察到高水平的耐药性是对 gentamicin (59.1%),zylpenicillin (30.9%) 和 nitrofurantoin (23.3%) 的.
- 多药耐药 (MDR) 菌株占隔离物的33.67%.
结论:
- 肠球菌 (Enterococcus faecalis) 在尿路感染中很常见.
- 高水平的 gentamicin 耐药性是一个重大问题.
- 观察到的多重耐药性模式需要对尿路感染进行仔细的抗菌疗法选择.
- 储备抗生素如线索利德,万科米辛和提科普拉宁需要谨慎使用.
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