"探索纽带":糖尿病与非糖尿病人群中的慢性肌肉骨疼痛
Owais Ahmed1, Suresh R Prabhu2, Ajoy Prasad Shetty3
1Department of Orthopaedics and Trauma, Ganga Medical Center & Hospital, Coimbatore, India.
Journal of orthopaedics
|November 20, 2024
概括
糖尿病患者患有较高的慢性肌肉骨疼痛率,与HbA1c水平升高显著相关. 使用简单问卷进行早期查可以帮助管理疼痛并预防糖尿病患者的并发症.
科学领域:
- 内分泌学 在内分泌学.
- 类风湿病学 类风湿病学
- 疼痛医学 医学 疼痛医学
背景情况:
- 糖尿病 (DM) 是一个全球性的健康问题,与由于糖化最终产品而导致的硬和肌肉骨疼痛等并发症有关.
- 肌肉骨疼痛是一种常见的,经常被忽视的DM并发症,疼痛机制被分为痛感性,神经性,痛感性和异常类型.
研究的目的:
- 为了确定2型糖尿病患者慢性肌肉骨 (cMSK) 疼痛的患病率.
- 调查cMSK疼痛,血糖控制 (HbA1c,RBS) 和糖尿病患者的并发症之间的关联.
- 在糖尿病人群中评估与cMSK疼痛相关的并发症.
主要方法:
- 一项前性病例控制研究,涉及300名2型糖尿病患者 (研究组) 和300名年龄相匹配的健康对照.
- 数据收集包括临床病史,并发症,HbA1c,随机血糖 (RBS) 和cMSK疼痛评估,使用修改后的北欧标准问卷.
- 进行了统计分析,以评估cMSK疼痛,糖尿病和血糖控制参数之间的关联.
主要成果:
- cMSK疼痛的总体患病率为23.3%,糖尿病组为27.7%,健康队列为19% (几率比=1.6).
- 在cMSK疼痛和HbA1c水平 (p<0.005) 之间发现了显著的关联,HbA1c>12的个体在多个区域报告疼痛.
- 没有观察到cMSK疼痛与糖尿病,高血压,脂质不良或甲状腺功能低下之间有显著的关联 (P>0.05).
结论:
- 慢性肌肉骨疼痛在糖尿病患者中更为普遍,并且与较差的血糖控制显著相关.
- 有效管理肌肉骨疼痛对于改善糖尿病患者的生活质量至关重要.
- 使用简单问卷进行cMSK疼痛的常规查,可以帮助糖尿病患者早期检测和预防并发症.
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