住院精神病患者的不良药物反应,患病率,严重程度,可预防性和干预机会
Asma Al Hindi1, Sara Al Balushi2, Sharifa Al Ruzaiqi3
1Pharmacy Department, Royal Hospital, Muscat, Oman.
Oman medical journal
|November 20, 2024
概括
这项研究强调了精神病医院中与精神药物相关的不良药物反应 (ADRs) 的普遍性,强调了加强药物监测和药剂师参与患者安全的必要性. 神经和激素的副作用很常见,联合治疗增加了风险.
科学领域:
- 药物监督 药物监督 药物监督
- 精神病学是一个精神病学.
- 临床药房 临床药房
背景情况:
- 药物不良反应 (ADRs) 是精神病治疗中的一个重要问题,影响患者的安全和治疗坚持.
- 药剂师在预防,检测和管理ADR方面发挥着至关重要的作用,特别是在心理药物方面.
研究的目的:
- 加强精神病学转诊医院的药监活动.
- 在住院患者中识别与精神药物相关的ADR模式.
- 评估有害反应的因果关系,严重程度和管理,并建立报告平台.
主要方法:
- 接受精神药物治疗的成年患者 (18-60岁) 在13个月的时间内被招募.
- 排除标准包括药物滥用,怀孕和克洛扎使用.
- 分析了ADR的因果关系 (纳兰乔的算法),严重程度 (哈特维格和西格尔) 和可预防性 (舒莫克和桑顿).
主要成果:
- 在506名患者中,217名 (42.9%) 患者中记录了327个可疑的副作用.
- 神经性ADR是最常见的 (47.4%),其次是心血管性 (18.7%) 和荷尔蒙性 (15.0%).
- 联合治疗增加了ADR风险,而单一治疗与心血管和神经系统的ADR有关. 荷尔蒙性ADR在男性中较高,女性的神经性ADR较高.
结论:
- 精神病学中多学科的ADR监测可以改善早期检测和患者的遵守.
- 基于医院的报告系统对于医疗保健专业人员进行自发和积极的ADR评估至关重要.
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