饮食和体育活动的修改:对患有唐氏综合征的儿童适应性行为和生化措施的影响
Ayman Kilany1,2, Mohamed E Elhadidy1, Mona M F Ganem3
1Research on Children with Special Needs Department, Medical Research and Clinical Studies Institute, National Research Centre, Cairo, Egypt.
International journal of developmental disabilities
|November 20, 2024
概括
通过饮食和运动减轻体重可以改善唐氏综合征 (DS) 和肥胖儿童的适应性行为和生化标志物. 将营养修改与物理治疗结合起来,可以为患有DS的儿童带来更好的结果.
科学领域:
- 儿科 儿科 儿科
- 遗传学 是一个遗传学.
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 唐氏综合征 (DS) 儿童的肥胖与不良行为结果有关.
- 需要有效的干预措施来管理肥胖及其相关的健康问题.
研究的目的:
- 评估减肥干预措施对DS肥胖儿童适应性行为和生化标志物的影响.
- 为了比较单独的饮食修改与与物理治疗相结合的饮食修改的有效性.
主要方法:
- 招募了100名患有DS和肥胖症的儿童 (年龄为6-9岁).
- 参与者被随机分为两组:仅饮食修改 (I组) 或饮食修改与运动 (II组).
- 评估了适应性行为 (Vineland尺度) 和生物化学标记 (脂质,炎症性细胞因子).
主要成果:
- 减肥导致了适应性行为得分的提高和脂质样本的有利变化 (降低甘油三,增加HDL-C).
- 在这两组中,炎症标志物 (联素-1,联素-6,勒素) 的水平都下降了.
- 与I组 (单独饮食) 相比,II组 (饮食+运动) 的测量结果明显改善.
结论:
- 减肥对适应性行为,脂质障碍和DS的肥胖儿童的炎症有好处.
- 与饮食修改相比,将体育活动与营养修改相结合,为患有DS的肥胖儿童提供了优越的健康和行为益处.
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