响应抑制作为一种关键的执行功能,用于区分注意力缺陷/多动症与自闭症谱系障碍:一项全面的注意力测试研究
Kangto Lee1,2, In Hee Cho1,2, Jeonghoon Park1,2
1Department of Child and Adolescent Psychiatry, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Frontiers in psychiatry
|November 20, 2024
概括
减弱的反应抑制在注意力缺陷/多动障碍 (ADHD) 中比自闭症谱系障碍 (ASD) 更明显. 这项研究表明,视觉注意力变化可能会使这些情况发生差异化,同时出现的情况会显示出附加效应.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 临床心理学 临床心理学
背景情况:
- 自闭症谱系障碍 (ASD) 和注意力缺陷/多动障碍 (ADHD) 分享执行功能障碍,特别是在复杂的注意力方面.
- 以前的临床评估在区分这些疾病方面得出了不确定的结果.
- 本研究使用统一的计算机测试来调查内类表型差异.
研究的目的:
- 阐明ASD,ADHD和它们同时出现的疾病 (ASD+ADHD) 之间的内类表型差异.
- 通过注意力评估,识别潜在的内基类型标记物来区分ADHD和ASD.
- 探索ASD患者同时出现的ADHD的附加效应.
主要方法:
- 包括被诊断为ASD (n=112),ASD+ADHD (n=155) 或ADHD (n=104) 的儿童.
- 使用综合注意力测试 (CAT) 并排除智力障碍或其他主要神经/精神伴随性疾病的参与者.
- 采用多变量线性回归来对CAT测量和父报告尺度进行探索性分析.
主要成果:
- 与ASD+ADHD和ADHD组相比,ASD组的佣金错误 (CE) 和坚持错误 (PE) 比ASD组更高.
- 在ASD+ADHD和ADHD组中,反应时间 (RT) 和社会沟通问卷 (SCQ) /儿童行为检查清单 (CBCL) 外化得分之间发现了显著的负相关性.
- 与ASD+ADHD组相比,ASD+ADHD组反应时间 (RTSD) 的标准偏差较高.
结论:
- 与ASD相比,ADHD中受损反应抑制更为明显.
- 改变视觉注意力,反映反应抑制,可能作为潜在的内类表型标志物,区分ADHD和ASD.
- 在ASD+ADHD组中增加的RTSD表明了附加性病理以及持续注意力缺陷潜在不同的潜在神经系统机制.
关键词:
更多关于 ADHD ADHD 的文章自闭症谱系障碍 自闭症谱系障碍孩子们的孩子们的孩子们的孩子们.伴随性疾病发生率.综合注意力测试试验 综合注意力测试执行职能 执行职能是指执行职能.反应抑制抑制的反应.更多相关视频
10:02Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
Published on: March 12, 2020
15.6K
05:32Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos
Published on: December 7, 2018
8.9K
相关概念视频
01:30Attention-Deficit/Hyperactivity Disorder
42
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
42
01:19Autism Spectrum Disorder
64
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
64