在子宫内膜异位症患者中患有未诊断的铁缺乏症的高患病率:一个横截面研究
Hanna R Goldberg1, Carmen McCaffrey1,2, Jonathon Solnik1,3
1Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada.
概括
超过一半的子宫内膜异位症患者有未被诊断的铁缺乏症,这会影响她们的福祉. 这种常见的疾病,铁缺乏症,需要在妇科护理中给予更大的临床关注.
科学领域:
- 生殖医学 生殖医学
- 血液学 血液学 血液学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 子宫内膜异位症是一种慢性炎症性妇科疾病,影响生殖年龄的女性.
- 缺铁是一种常见的伴随性疾病,与慢性疾病和显著的症状负担相关.
研究的目的:
- 为了确定被诊断为子宫内膜异位症的妇女中未被诊断的铁缺乏症的患病率.
- 探索铁缺乏与患者报告的症状,包括疲劳和大量月经出血之间的关联.
主要方法:
- 进行了一项多中心的横截面研究,对251名年龄在18-50岁的妇女进行了诊断为症状性子宫内膜异位症的研究.
- 参与者接受了血液检查,以检测铁状况 (费里丁,转激素和),并填写了关于人口统计,病史和症状的验证问卷.
- 统计分析比较了群体之间的铁缺乏患病率和症状得分.
主要成果:
- 在子宫内膜异位症队列中,缺铁的患病率为53.4% (134/251).
- 铁缺乏症在有大量月经出血的患者中更为常见 (49.6%),但在没有大量月经出血的患者中也更为普遍 (47%).
- 铁缺乏症患者报告生活质量明显降低,特别是疲劳得分更高 (p=0.025).
结论:
- 大部分患有子宫内膜异位症的女性没有被诊断出缺铁.
- 缺铁严重影响了这一群体的疲劳和整体幸福感.
- 建议对患有子宫内膜异位症的妇女进行常规铁缺乏症查,无论她们报告有多重月经出血.
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