在瑞典一般人口中,与时间和自我感知年龄相关的血管衰老
Madeleine Johansson1,2, Stefan Söderberg3, Peter M Nilsson1
1Department of Clinical Sciences, Lund University, Malmö, Sweden.
Scandinavian cardiovascular journal : SCJ
|November 20, 2024
概括
感觉比你的年龄年轻可能表明更好的血管健康,特别是在45岁以下的成年人. 这项研究将自我感知的年龄与大动脉硬性联系起来,这是血管衰老的标志.
科学领域:
- 心血管健康 心血管健康
- 衰老研究研究 衰老研究
- 精神病体医学是一种精神病体医学.
背景情况:
- 大动脉硬是血管衰老的一个关键指标.
- 血管衰老的非传统标志物仍未得到充分探索.
- 这项研究探讨了主观年龄感知与大动脉硬度之间的联系.
研究的目的:
- 检查自我感知年龄 (SPA) 和自我评估健康 (SRH) 与大动脉硬度之间的关联.
- 在一般人口样本中探索这些关系.
- 为了确定血管衰老的潜在主观标志物.
主要方法:
- 对来自瑞典队列的3760名参与者的横截面研究.
- 通过自我报告的年龄与同龄人 (SPA-self,SPA-others) 相比评估SPA.
- 大动脉硬度是用动脉-大腿脉冲波速率 (PWV) 来测量的.
主要成果:
- 年轻的成年人 (≤45岁) 患有较老的SPA-其他人显示PWV较低,表明血管衰老较少.
- 这种反向关系也在45岁以下的女性中观察到,年龄较大的SPA-self.
- 老年人 (>45岁) 患有低SRH和老年SPA-其他人表现出增加的血管衰老 (更高的PWV).
结论:
- 自我感知年龄是一个主观的认知因素,与血管衰老相反.
- 这种关联在时间上较年轻的成年人 (≤45岁) 中尤为明显.
- 主观年龄感知可以作为血管衰老轨迹的新指标.
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