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Updated: Jun 7, 2025

Epigenetic Conversion as a Safe and Simple Method to Obtain Insulin-secreting Cells from Adult Skin Fibroblasts
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葡萄糖结合并激活NSUN2以促进翻译和表皮分化

Weili Miao1, Douglas F Porter1, Ya Li2

  • 1Program in Epithelial Biology, Stanford University School of Medicine, 269 Campus Dr, Stanford, CA 94305, USA.

Nucleic acids research
|November 20, 2024
PubMed
概括

细胞内葡萄糖的升高对于上皮细胞的分化至关重要. 葡萄糖直接结合并增强RNA结合蛋白NSUN2,通过调节信使RNA转化来增强其活性和促进分化.

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