炎症标志物与手术后增强恢复 (ERAS) 之间的相关性 在腹腔镜切除术中失败
Ji Hyeong Song1, Yoonsoo Shin2, Kyung Ha Lee3
1Department of Surgery, Inje University Haeundae Paik Hospital, Busan, Korea.
Surgery today
|November 20, 2024
概括
某些炎症标志物,特别是C反应性蛋白与白蛋白比率 (CAR),可以预测经过腹腔镜切除术的患者在手术 (ERAS) 失败后的增强恢复. 监测这些标志物有助于识别有风险的个体,以改善患者的治疗结果.
科学领域:
- 手术成果研究的研究结果.
- 分析炎症标志物的分析.
- laparoscopic colectomy 患者分层 拉皮眼切除术患者分层
背景情况:
- 手术后增强恢复 (ERAS) 协议旨在优化患者手术后的恢复.
- 识别ERAS失败的预测因素对于积极的患者管理至关重要.
- 腹腔镜切除术是一种常见的外科手术,经常采用ERAS协议.
研究的目的:
- 为了评估特定的炎症标志物作为腹腔镜切除术后ERAS失败的预测因素.
- 为了确定在手术后出现低最佳恢复风险较高的患者.
- 为了确定预测ERAS失败的最强烈的炎症标志物.
主要方法:
- 在2020年9月至2023年2月期间,对402名接受了腹腔镜切除术的患者进行了分析.
- 通过饮食不耐受,长时间住院 (>7天) 或30天再入院来定义ERAS失败.
- 测量炎症标志物 (中性粒细胞与淋巴细胞的比率,血小板与淋巴细胞的比率,单细胞与淋巴细胞的比率,C-反应蛋白与白蛋白的比率) 在术后 (POD) 0,1,3天.
主要成果:
- 在POD3上,中性粒细胞与淋巴细胞的比率,血小板与淋巴细胞的比率,单细胞与淋巴细胞的比率以及C反应蛋白与白蛋白的比率 (CAR) 的升高与ERAS失败有关.
- 在失败组中也观察到更高的立即术后CAR.
- 低体重指数 (<20),右结肠瘤和更长的手术时间等因素增加了ERAS失败的风险.
结论:
- 在腹腔镜切除术后,炎症标志物与ERAS失败有显著的关联.
- 反应性C蛋白与白蛋白的比率 (CAR) 显示了其作为预测ERAS失败的关键指标的潜力.
- 这些发现可以指导临床实践在识别和管理高风险患者.
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