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在酵母Hsp90中占主导地位的负基因突变表明,选决策机制针对客户端蛋白进行降解

Julia M Flynn1, Margot E Joyce1, Daniel N A Bolon1

  • 1Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605.

Molecular biology of the cell
|November 20, 2024
PubMed
概括

在酵母Hsp90中确定了主要的负基因突变. 这些突变破坏了蛋白质结构和客户端蛋白质降解,为Hsp90机制提供了洞察力.

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