被转诊机构接收的急性腹马的治疗方法:一个多中心的回顾性研究
Diego E Gomez1, Jamie J Kopper2, David P Byrne3
1Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
PloS one
|November 20, 2024
概括
治疗急性腹的马的治疗方法在全球范围内有所不同,流体治疗和抗菌药物是常见的. 需要进一步的试验来确定马匹急性腹的最佳治疗方法.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 马的健康 马的健康
- 胃肠病学 胃肠病学
背景情况:
- 急性腹是马匹的重大健康问题.
- 了解全球治疗策略对于改善马类护理至关重要.
研究的目的:
- 在不同地理区域描述和比较患有急性腹的马的治疗干预措施.
- 根据地点和季节,识别治疗方案的变化.
主要方法:
- 在26个国际机构 (2016-2020年) 追溯收集腹马的临床数据.
- 管理治疗的分析,包括流体治疗,抗微生物药物,益生菌和支持性护理.
- 研究季节性和地理因素对治疗选择的影响.
主要成果:
- 其中包括1438匹马,65%在入院时接受了液体玻尿酸.
- 55%的马在24小时内服用了抗菌药物,通常是青素和 gentamicin.
- 白血病和SIRS标准增加了抗微生物药物治疗的几率; 其他治疗包括益生菌,胃保护剂和数字冷疗法.
结论:
- 在不同地理区域之间,马匹急性腹治疗方案存在显著差异.
- 追溯设计限制了对治疗理由和生存关联的评估.
- 预期的临床试验对于评估各种治疗对生存率的有效性至关重要.
相关概念视频
Drugs for Treatment of Diarrhea-Predominant IBS
147
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
147
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
109
Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
109
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
317
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
317
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
328
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
328
Peptic Ulcer Disease IV: Management
74
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
74


