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Updated: Jun 7, 2025

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基于PTCy的移植与宿主疾病预防,用于匹配的兄弟捐赠者全源造血细胞移植

Nihar Desai1,2, Majed Altareb1,2, Mats Remberger3

  • 1Hans Messner Allogeneic Blood and Marrow Transplant Program, Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Canada.

Blood advances
|November 20, 2024
PubMed
概括

移植后的环胺 (PTCy) 通过减少移植对宿主疾病 (GVHD) 和死亡率,显著改善了匹配的兄弟捐赠者血造干细胞移植 (HSCT) 的结果. 在不增加复发风险的情况下,PTCy可提高无GVHD/无复发生存率 (GRFS).

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