低乳腺密度与心上脂肪组织体积和冠状动脉疾病有关
Emma Aldous1, Vinay Goel2, Chee Yeong2
1Monash University, Wellington Rd, Clayton 3800, Melbourne, Victoria, Australia; Victorian Heart Hospital, Blackburn Rd, Clayton 3800, Melbourne, Victoria, Australia.
女性乳腺密度低与心上脂肪组织体积 (EATv) 的增加有关,并独立预测冠状动脉疾病 (CAD). 乳房扫描乳腺密度可以作为早期CAD风险指标.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 妇女健康 妇女健康
背景情况:
- 心脂肪组织体积 (EATv) 与冠状动脉疾病 (CAD) 相对应.
- 乳房扫描乳腺密度可能反映心脏代谢风险.
- 较高的乳腺脂肪度与心血管风险增加有关.
研究的目的:
- 评估乳腺密度,EATv和CAD之间的关联.
- 确定乳腺密度是否可以作为女性CAD早期风险识别工具.
主要方法:
- 对153名接受冠状动脉计算机断层扫描血管造影 (CCTA) 和乳房扫描的妇女进行了回顾性,横截面研究.
- 使用半自动化软件量化了EATv.
- 乳腺密度通过BI-RADS分级评估;CAD按存在,缺席和严重程度分类 (CAD-RADS).
主要成果:
- 在67.3%的女性中观察到乳腺密度低 (脂肪度高).
- 低乳腺密度与年龄较大,高血压,高BMI和显著更高的EATv (p < 0.001) 相关.
- 低乳腺密度独立预测了CAD的存在 (OR:3.21) 并与更高的EATv相关.
结论:
- 低乳房乳腺密度与EATv增加有关,并独立预测CAD.
- 乳腺密度可能是女性早期CAD风险识别的宝贵工具.
- 研究结果表明,脂肪分布和心血管风险之间存在联系.
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