用酸盐和酸盐 (SNaP) 稳定的酸牙膏对牙过敏的影响:体外研究和随机对照试验
Yangxi Liu1, Stacey Lavender2, Farid Ayad3
1Senior Research Scientist Research and Development, Colgate-Palmolive Co., Piscataway, New Jersey.
概括
一种新的化牙膏 (SNaP) 有效地遮住牙管道,并从使用的第一天起显著减少牙过敏性疼痛. 这种先进的配方可以长期缓解敏感性,改善口腔健康.
科学领域:
- 口腔健康 口腔健康
- 丹丁的过敏性研究研究.
- 牙科治疗学 牙科治疗学
背景情况:
- 牙过敏是一种广泛存在的口腔健康问题.
- 这项研究评估了一种用酸盐和酸盐 (SNaP) 稳定的新型化牙膏.
研究的目的:
- 评估SNaP牙膏在堵塞牙管道中的有效性.
- 在临床环境中使用SNaP评估牙过敏症的减少.
主要方法:
- 在SNaP牙膏对牙封闭的体外测试与对照.
- 一个III期随机对照试验,涉及120名参与者.
- 在基线,第一天,第三天和第七天通过触觉和空气爆炸刺激评估牙过敏性.
主要成果:
- 在体外,SNaP实现了86%的管管封闭,而对照组为35% (P < .05).
- 7天后,SNaP显著降低了触觉过敏,79.8% (相对于阳性对照) 和90.2% (相对于负面对照) (P < .001).
- 从第一天开始,SNaP显著减少了空气爆炸过敏 (47.1%和47.9%与对照组相比,P < .001),并减少了疼痛.
结论:
- SNaP牙膏有效地覆盖牙,遮住管道,并提供快速,提高敏感度的缓解.
- 多益配方改善日常生活,促进口腔健康,并可能预防未来的牙问题.
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