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Updated: Jun 7, 2025

Using Mouse Oocytes to Assess Human Gene Function During Meiosis I
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遗传不育:绘制与女性生殖能力受损相关的位置

Sanni Ruotsalainen1, Juha Karjalainen2, Mitja Kurki2

  • 1Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.

American journal of human genetics
|November 20, 2024
PubMed
概括

一种罕见的TBPL2基因突变显著增加了女性不孕症风险. 这项全基因组研究还确定了与早期和晚期不孕症相关的遗传因素,突出了罕见的衰减等位基因和年龄相关机制.

关键词:
这是TBPL2的TBPL2.女性不孕症女性不孕症全基因组关联研究研究.这是一种衰退式继承.切断突变的发生.

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