生物材料接口和药物输送的最新发展:挑战,创新和未来前景
Saraswati Patel1, Samsi D Salaman2, Devesh U Kapoor3
1Department of Pharmacology, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Thandalam, Chennai, 602105, Tamil Nadu, India.
Zeitschrift fur Naturforschung. C, Journal of biosciences
|November 20, 2024
概括
生物材料通过优化有效载荷和释放以获得更好的治疗结果来彻底改变药物输送. 了解和调节生物材料接口是克服输送障碍和提高药物有效性的关键.
科学领域:
- 生物材料科学 生物材料科学
- 药物输送系统 药物输送系统
- 纳米技术 纳米技术
背景情况:
- 药物输送领域在生物材料的推动下取得了重大进展.
- 生物材料具有生物相容性和生物降解性,这对于有效的药物输送至关重要.
- 生物材料的接口特性受到物理化学属性,生理障碍,细胞贩运和免疫调节效应的影响.
研究的目的:
- 审查生物材料及其在药物输送中的接口的有效性.
- 探索减轻和调节障碍和物理化学性质的方法.
- 检查基于生物材料的药物输送的未来前景.
主要方法:
- 关于生物材料在药物输送中的应用的文献综述.
- 分析影响生物材料界面相互作用的因素.
- 讨论克服生理和免疫障碍的策略.
主要成果:
- 生物材料通过优化有效载荷和释放动力学来显著增强药物输送系统.
- 通过物理化学性质调节和免疫掩盖来调节生物界面,提高了药物的疗效.
- 将现有药物重新用于新的适应症是一种由先进生物材料技术促进的日益增长的趋势.
结论:
- 生物材料在推进药物输送方面发挥着关键作用,提供了改善的治疗指数和减少副作用.
- 有效调节生物材料接口对于克服生物障碍至关重要.
- 未来的研究应该专注于创新的超分子结构和使用生物材料的药物重新利用.
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