在患有恶性瘤的患者中,识别瘤管相关的肺炎的致病和非致病微生物
Norihiko Terada1, Shigemi Hitomi2, Hanako Kurai3
1Department of Infectious Diseases, Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan; Division of Infectious Diseases, Department of Medicine, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, Tsukuba, Ibaraki, 305-8558, Japan.
概括
瘤管相关的肺炎 (NTAP) 在癌症患者中很常见. 大肠杆菌常常导致NTAP,但尿液培养中的一些抗素的生物可能不需要抗菌治疗.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 在瘤学瘤学.
背景情况:
- 长时间使用nephrostomy管可以导致管相关的肺炎 (NTAP).
- 癌症患者通常需要长期使用瘤管,从而增加NTAP的易感性.
- 有限的数据存在于癌症患者的NTAP特征.
研究的目的:
- 在患有恶性瘤的患者中表征瘤管相关性肌炎 (NTAP).
- 识别致病微生物并评估抗微生物治疗的必要性.
主要方法:
- 在癌症患者中对43例NTAP病例的回顾性审查.
- 分析尿液和血液培养物,以区分致病微生物和非致病微生物.
- 根据培养结果和抗微生物治疗持续时间,定义了致病微生物.
主要成果:
- 大多数患者 (42/43) 通过抗微生物药物治疗恢复过来.
- 大肠杆菌和Klebsiella pneumoniae是最常见的致病生物体.
- 某些生物体,如Enterococcus物种和Candida物种,往往是非致病的.
结论:
- 大肠杆菌是癌症患者中NTAP的常见原因.
- 在尿液中检测到的一些抗塞法洛斯波林的微生物可能不需要治疗.
- 仔细评估尿液培养对于适当的NTAP管理至关重要.
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