相关实验视频

Updated: Jun 7, 2025

Towards Biomimicking Wood: Fabricated Free-standing Films of Nanocellulose, Lignin, and a Synthetic Polycation

Towards Biomimicking Wood: Fabricated Free-standing Films of Nanocellulose, Lignin, and a Synthetic Polycation

Published on: June 17, 2014

生物细胞壁模型:利用TEMPO氧化纤维素纳米纤维用于富可桑输送系统

Fang Tian¹, Shuyi Xu¹, Miaoyu Gan²

¹Key Laboratory of Health Risk Factors for Seafood of Zhejiang Province, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China; Ningbo Innovation Center, College of Biosystems Engineering and Food Science, Zhejiang University, Ningbo 315100, China.

Carbohydrate polymers

|November 20, 2024

概括

这项研究使用氧化纤维素开发了一种生物细胞壁,以改善富可桑 (FX) 的生物可用性. 新型载体在胃中保护FX,并在肠道中释放.

科学领域:

生物材料科学生物材料科学
药物输送系统药物输送系统
营养保健品营养保健品

背景情况:

富可丁 (FX) 具有显著的生物益处,但由于口服生物可用性较差而受到限制.
开发有效的输送系统对于最大限度地发挥FX的治疗潜力至关重要.

研究的目的:

为了设计一种新的生物细胞壁模型,以增强富可桑的输送.
为了提高脂质体福可桑丁的稳定性和受控释放.

主要方法:

使用TEMPO氧化纤维素制造生物细胞壁.
在脂质体内封装富可丁.
在模拟的胃和肠道条件下评估脂质体稳定性和FX释放.

主要成果:

在TEMPO氧化纤维素生物细胞壁显著提高了脂肪体在酸性环境中的稳定性.
生物细胞壁在模拟的肠液中表现出pH响应的释放,分散和释放富可桑丁.
保护层在模拟的胃条件下防止了脂质体和富可桑丁的降解.

结论:

基于纤维素的生物细胞壁显示出稳定和输送生物活性化合物,如fucoxanthin.
这种方法为设计功能成分的先进载体提供了一个多功能平台.
开发的系统解决了富可桑的生物可用性挑战,为改善其利用铺平了道路.

关键词:

富可桑丁是一种富可桑丁 (fucoxanthin) 的成分.脂质体是一种脂质体.稳定的稳定性稳定的稳定性时间氧化纤维素纳米纤维.

更多相关视频

Isolating and Incorporating Light-Harvesting Antennas from Diatom Cyclotella Meneghiniana in Liposomes with Thylakoid Lipids

Isolating and Incorporating Light-Harvesting Antennas from Diatom Cyclotella Meneghiniana in Liposomes with Thylakoid Lipids

Published on: August 28, 2018

Bacterial Cellulose Spheres that Encapsulate Solid Materials

Bacterial Cellulose Spheres that Encapsulate Solid Materials

Published on: February 26, 2021

相关概念视频

Cellulose and Pectic Polysaccharides

Cellulose and Pectic Polysaccharides

Every plant cell has a cell wall that protects the cell, provides structural support, and gives the cell shape. Cellulose, the main structural component of the plant cell wall, makes up over 30% of plant matter. It is the most abundant organic compound on earth. Cellulose is an unbranched polysaccharide composed of linear chains of glucose molecules linked by β (1→4) glycosidic bonds.
As a cell matures, its cell wall specializes according to its type. For example, the...

Role of Microtubules in Cell Wall Deposition

Role of Microtubules in Cell Wall Deposition

Microtubules are small hollow tubes in eukaryotic cells. The cell wall microtubules are polymerized dimers of two globular proteins, α-tubulin and β-tubulin, two globular proteins. With a diameter of about 25 nm, microtubules are the widest components of the cytoskeleton. They help the cell resist compression and provide a track along which vesicles move through the cell or pull replicated chromosomes to opposite ends of a dividing cell. Microtubules go through quick cycles of...