摄入前后多醇和卵巢癌存活率:来自前性队列研究的证据
Jia-Nan Sun1, Yu Li1,2, Meng Luan1
1Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
European journal of nutrition
|November 20, 2024
概括
饮食中摄入更多的多,包括黄类药物,与改善卵巢癌 (OC) 存活率有关. 在诊断后维持多的消费对于改善OC患者的整体存活率至关重要.
科学领域:
- 营养瘤学 营养瘤学
- 流行病学 流行病学
- 癌症研究 癌症研究
背景情况:
- 多具有抗癌性质,但它们对卵巢癌 (OC) 存活率的具体影响尚未得到充分证实.
- 了解影响OC存活的饮食因素对于开发有效干预措施至关重要.
研究的目的:
- 研究卵巢癌 (OC) 患者的饮食中多摄入量和整体存活率 (OS) 之间的关联.
- 为了检查在诊断前和之后的多摄入量,以及与OC存活率相关的诊断前和后摄入量的变化.
主要方法:
- 一项前性队列研究,涉及560名OC患者.
- 通过使用经过验证的食物频率问卷,评估了总 (多) 和五个类的饮食摄入量.
- 使用考克斯比例危险回归模型分析了整体生存 (OS).
主要成果:
- 在诊断前和诊断后摄入较高的多醇与OC患者的死亡风险降低显著相关.
- 在聚enol/flavonoid摄入量和改善OC存活率之间观察到一个线性趋势.
- 诊断后降低多醇摄入量与更糟糕的整体存活率 (OS) 有关.
结论:
- 总 (多) 和其主要类的饮食摄入量表明与卵巢癌 (OC) 存活率有相反的关联.
- 这些发现凸显了饮食中的多在改善OC患者治疗结果方面的潜在作用.
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