皮肤菌:临床流行病学和治疗的最新情况
Aleksandra Barac1,2, Mihailo Stjepanovic3,4, Snjezana Krajisnik4
1Clinic for Infectious and Tropical Diseases, University Clinical Center of Serbia, Belgrade, Serbia. aleksandrabarac85@gmail.com.
Mycopathologia
|November 20, 2024
概括
皮肤菌菌感染影响全球25%的人口,在Trichophyton indotineae.等物种中发现了对terbinafine的抗性增加. 解决这种日益严重的公共卫生问题需要了解不断变化的治疗挑战和耐药性模式.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 皮质菌在全球引起常见的真菌感染,影响25%的人口.
- 特里科菲顿 (Trichophyton rubrum) 是占主导地位的物种,导致各种虫感染.
- 像T. indotineae这样的新兴菌株表现出对terbinafine的耐药性,这给治疗带来了挑战.
研究的目的:
- 审查皮肤菌感染的流行病学和临床意义.
- 为了突出抗药性菌株的日益流行.
- 讨论当前和未来皮肤植物病的治疗策略.
主要方法:
- 关于皮肤菌感染的流行病学数据的文献综述.
- 临床案例研究和耐药性模式的分析.
- 综合关于抗真菌治疗和公共卫生影响的信息.
主要成果:
- 在全球范围内,Trichophyton rubrum仍然是皮肤植物病的主要原因.
- 观察到对特尔比纳耐药性T. indotineae和T. interdigitale (以前是T. mentagophytes基因型VII) 的发病率增加.
- 毛病 (onychomycosis) 在发达国家普遍存在,而毛病 (tinea capitis) 在发展中国家更加普遍.
结论:
- 皮肤菌感染对全球健康构成重大负担.
- 抗真菌耐药性和反复感染是越来越多的公共卫生问题.
- 持续监测和开发有效的治疗策略至关重要.
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