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Updated: Jun 7, 2025

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UBXN9控制RIG-I类受体的GLUT4介导空间限制和信号传输

Andrew G Harrison1, Duomeng Yang2,3, Jason G Cahoon1

  • 1Department of Immunology, School of Medicine, University of Connecticut Health Center, Farmington, CT, USA.

Nature immunology
|November 20, 2024
PubMed
概括

胰岛素敏感的GLUT4蛋白通过隔离RIG-I类受体 (RLRs) 来抑制病毒RNA传感. 这种涉及UBXN9的新型机制影响了先天的抗病毒免疫力,并与炎症性肌肉病变有关.

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