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Updated: Jun 7, 2025

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
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Il4-Il13-Il5位点的重塑是选择性基因表达的基础

Hiroyuki Nagashima1, Justin Shayne2, Kan Jiang3

  • 1Lymphocyte Cell Biology Section, NIAMS, NIH, Bethesda, MD, USA. hiroyuki.nagashima@nih.gov.

Nature immunology
|November 20, 2024
PubMed
概括

监管要素控制2型细胞因子基因表达. 它们的三维组织在细胞激活时发生变化,影响了白内素 (IL) -4,IL-5和IL-13的产生和免疫反应.

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