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Updated: Jun 7, 2025

Reverse Genetics to Engineer Positive-Sense RNA Virus Variants
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Reverse Genetics to Engineer Positive-Sense RNA Virus Variants

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病毒N蛋白劫持了含有脱氨酶的RNA颗粒,以增强SARS-CoV-2的突变发生

Zhean Li1,2, Lingling Luo3,4, Xiaohui Ju5

  • 1Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China.

The EMBO journal
|November 20, 2024
PubMed
概括

主体去氨酶,APOBEC和ADAR,驱动SARS-CoV-2突变,阻碍病毒复制. 病毒核体蛋白与这些脱氨酶相互作用,促进突变发生,并提供对病毒与宿主相互作用的见解.

关键词:
脱氨基酶是一种脱氨基酶.具有天生的免疫力.突变发生是突变发生的.这就是SARS-CoV-2病毒.

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