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Updated: Jun 7, 2025

An In Ovo Model for Testing Insulin-mimetic Compounds
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An In Ovo Model for Testing Insulin-mimetic Compounds

Published on: April 23, 2018

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设计新的类似物,它们比原生激素,胰岛素样5 (INSL5) 更具受体选择性和强度

Hongkang Wu1, Herodion A Hartono2, Thomas N G Handley1

  • 1Florey Institute of Neuroscience and Mental Health and Florey Department of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3052, Australia.

Journal of medicinal chemistry
|November 21, 2024
PubMed
概括

研究人员开发了一种简化的胰岛素类5 (INSL5) 模拟物A13:B7-24-GG,用于治疗便秘. 这种新型更容易合成,更强效,并且对其向受体RXFP4.4具有选择性.

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