在高血压的临床管理中进行化学依从性测试:范围审查
Louise Rabbitt1,2, James Curneen1,2, Michael Conall Dennedy1,2
1Department of Pharmacology, School of Medicine, University of Galway, Galway, Ireland.
Frontiers in pharmacology
|November 21, 2024
概括
用于高血压管理的化学附着性测试 (CAT) 显示了各种应用,需要标准化的定义. 更多的随机对照试验对于评估其临床影响和效用至关重要.
科学领域:
- 药理学 药理学是指药理学的学科.
- 临床医学 临床医学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 在高血压管理中越来越多地使用化学附着性测试 (CAT) 引发了关于其实用性,可接受性和可行性的疑问.
- 目前的临床实践缺乏在高血压中应用CAT的标准化.
- 现有研究强调了CAT实施和定义的变化.
研究的目的:
- 识别和总结使用CAT在高血压管理中的研究.
- 批判性地评估CAT在高血压管理中的当前临床应用.
主要方法:
- 对同行评审的英语研究进行了范围审查,报告了原始研究.
- 在Ovid Medline,EMBASE和PsycInfo中进行的搜索,并通过手动参考列表搜索来补充.
- 使用Covidence软件对标题,摘要和全文文章进行选.
主要成果:
- 从最初的618个已识别的研究中,包括了48个研究.
- 研究涉及多种不同的临床环境,主要是观察性,很少有随机对照试验.
- 观察到术语,定义 (特别是坚持) 和理论框架的使用方面存在显著差异.
结论:
- 在实施CAT用于高血压管理方面存在相当大的变化.
- 随机对照试验的稀缺性阻碍了对CAT影响的评估.
- 未来的研究应该集中在标准化定义,理论框架和RCT上,以评估CAT的临床结果.
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