印度和中国的老年人中II型糖尿病和认知功能 - - 根据协调认知评估协议研究的结果
Subidsa Srikantha1, Jennifer Manne-Goehler2, Lindsay C Kobayashi3,4
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Frontiers in public health
|November 21, 2024
概括
在印度和中国,II型糖尿病并没有影响一般认知能力,但根据农村/城市居住和教育水平,这种关联有所不同. 这些发现与高收入国家有所不同,这表明这些LMICs中存在独特的流行病学和营养模式.
科学领域:
- 全球健康 全球健康
- 神经科学是一个神经科学.
- 流行病学 流行病学
背景情况:
- 二型糖尿病是高收入国家认知能力下降的已知危险因素.
- 低收入和中等收入国家 (LMICs) 糖尿病与认知联系的研究有限.
- 了解不同人群中的这种关联对于公共卫生战略至关重要.
研究的目的:
- 调查和比较印度和中国老年人II型糖尿病和认知功能之间的关系.
- 探索城市与农村的居住和教育程度如何改变这种关联.
主要方法:
- 对印度 (n=4,062) 和中国 (n=9,741) 的协调认知评估协议研究的横截面数据的分析.
- 多变量调整的线性回归模型评估了糖尿病 (自我报告或HbA1c ≥6.5%) 和一般认知之间的关联.
- 相互作用测试检查了根据居住和教育对效果的修改.
主要成果:
- 在印度或中国的完全调整模型中,II型糖尿病与一般认知评分无关.
- 在印度,在农村居民中发现了积极的关联,但不是城市居民.
- 两国都显示了教育对效果的改变,在印度和中国之间观察到不同的模式.
结论:
- 印度和中国的II型糖尿病与认知功能之间的关联与高收入国家不同,可能是由于流行病学和营养过渡.
- 研究结果表明,诸如获得医疗保健,城市化和社会差距等因素可能会影响这种关系.
- 建议进行进一步的纵向研究,以探索这些复杂的关联,特别是在脆弱人群中.
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