勃起功能障碍和外围动脉疾病在NHANES 2001-2004年的关联:一个横截面研究
1Department of Interventional and Vascular Surgery, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, China.
Frontiers in endocrinology
|November 21, 2024
概括
勃起功能障碍 (ED) 与40岁以上美国男性患外围动脉疾病 (PAD) 的患病率较高有关. 这表明ED可能是PAD的独立预测因素,在患者治疗中需要考虑.
科学领域:
- 心血管健康 心血管健康
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
背景情况:
- 周围动脉疾病 (PAD) 是一种严重的血管疾病.
- 勃起功能障碍 (ED) 影响了相当一部分成年男性人口.
- 了解ED和PAD之间的关系对于评估心血管风险至关重要.
研究的目的:
- 研究成年美国男性勃起功能障碍 (ED) 和外周动脉疾病 (PAD) 之间的关联.
- 为了确定ED是否是PAD的独立预测因素.
主要方法:
- 利用了2001-2004年国家健康和营养检查调查 (NHANES) 的数据.
- 评估ED使用自我报告的勃起问题和PAD通过脚-手臂指数 (ABI) <0.9.
- 采用多因素后勤回归模型来分析关联,调整混变量.
主要成果:
- 总共有2394名参与者被分析,其中37.8%被诊断为ED.
- 在调整后,在ED和PAD (OR 2.05;95%CI 1.24-3.39) 之间发现了显著的积极关联.
- 亚组分析表明,这种关联在特定的人口结构中是显著的,包括50岁以上和没有某些并发症的人群.
结论:
- 勃起功能障碍 (ED) 与40岁及以上的美国成年人患外围动脉疾病 (PAD) 的发生率增加有关.
- 勃起障碍可以作为PAD的独立预测因素.
- 对于患有ED的患者,建议对PAD进行临床考虑.
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