基于空间相关性的二次性成本函数,用于通过散射介质塑造波
Amit Kumar1, Ayush Sharma1, S K Biswas1
1Indian Institute of Science Education and Research Mohali, Department of Physical Sciences, Bio-NanoPhotonics Lab, Manauli, Punjab, India.
Journal of biomedical optics
|November 21, 2024
概括
一个新的二次成本函数 (QCF) 在通过散射介质聚焦时精确控制光强度和均性. 这种先进的方法超越了传统的强度和峰值与背景比函数,用于改进光学控制.
科学领域:
- 光学和光子学 在光学和光子学.
- 生物医学成像技术 生物医学成像技术
- 材料科学 材料科学 材料科学
背景情况:
- 基于反的波面成型对于深层组织显微镜和生物化至关重要.
- 像强度和峰值与背景比率 (PBR) 这样的当前成本函数缺乏对焦点点的统一性和强度的精确控制.
- 通过散射介质准确聚焦光线具有挑战性,但对于各种应用来说至关重要.
研究的目的:
- 引入一种基于L2规范的二次性成本函数 (QCF),用于波面优化.
- 通过建立像素对像素强度和位置相关性,通过散射介质增强光的聚焦.
- 为了提高对比度优化和背景抑制在光学聚焦.
主要方法:
- 拟议的QCF与优化基因算法集成.
- 建立了像素对像素的相关性,以实现可控的对比度和均性.
- 进行模拟和实验验证,以将QCF与现有方法进行比较.
主要成果:
- QCF在精确的强度控制和焦点均性方面表现出卓越的表现.
- 与传统功能相比,提出的方法有效地抑制了背景强度.
- 模拟和实验证实了QCF在强度和PBR成本函数上的优势.
结论:
- QCF提供精确的强度控制,增强的均性和有效的背景抑制.
- 这种方法非常适合要求关键强度控制的应用,例如光刻法和剂量计.
- 在生物化和以后,QCF具有重要的能量调节潜力.
相关概念视频
Propagation of Waves
2.3K
When a wave propagates from one medium to another, part of it may get reflected in the first medium, and part of it may get transmitted to the second medium. In such a case, the interface of the two mediums can be considered as a boundary that is neither fixed nor free.
Consider a scenario where a wave propagates from a string of low linear mass density to a string of high linear mass density. In such a case, the reflected wave is out of phase with respect to the incident wave, however the...
Consider a scenario where a wave propagates from a string of low linear mass density to a string of high linear mass density. In such a case, the reflected wave is out of phase with respect to the incident wave, however the...
2.3K
Equations of Wave Motion
5.6K
Mathematically, the motion of a wave can be studied using a wavefunction. Consider a string oscillating up and down in simple harmonic motion, having a period T. The wave on the string is sinusoidal and is translated in the positive x-direction as time progresses. Sine is a function of the angle θ, oscillating between +A and −A and repeating every 2π radians. To construct a wave model, the ratio of the angle θ and the position x is considered.
5.6K
Curvilinear Motion: Rectangular Components
416
Curvilinear motion characterizes the movement of a particle or object along a curved path, notably evident when envisioning a car navigating a winding road. If the car starts at point A, its position vector is established within a fixed frame of reference, where the ratio of the position vector to its magnitude signifies the unit vector pointing in the position vector's direction.
As the car advances, its position evolves over time. Quantifying the car's velocity involves computing the...
As the car advances, its position evolves over time. Quantifying the car's velocity involves computing the...
416
Graphing the Wave Function
1.7K
Consider the wave equation for a sinusoidal wave moving in the positive x-direction. The wave equation is a function of both position and time. From the wave equation, two different graphs can be plotted.
1.7K
Plane Electromagnetic Waves I
3.6K
The existence of combined electric and magnetic fields that propagate through space as electromagnetic (EM) waves is the most significant prediction of Maxwell's equations. As Maxwell's equations hold in free space, the predicted electromagnetic waves do not require a medium for their propagation. An EM wave comprises an electric field, defined as the force per charge on a stationary charge, and a magnetic field, which is the force per charge on a moving charge.
The EM field is assumed...
The EM field is assumed...
3.6K
Linear Approximation in Frequency Domain
85
Linear systems are characterized by two main properties: superposition and homogeneity. Superposition allows the response to multiple inputs to be the sum of the responses to each individual input. Homogeneity ensures that scaling an input by a scalar results in the response being scaled by the same scalar.
In contrast, nonlinear systems do not inherently possess these properties. However, for small deviations around an operating point, a nonlinear system can often be approximated as linear....
In contrast, nonlinear systems do not inherently possess these properties. However, for small deviations around an operating point, a nonlinear system can often be approximated as linear....
85


