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Updated: Jun 7, 2025

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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将完全减少的多基酸合成酶重新用于2-甲基格尔贝特样脂质

Michael A Herrera1, Stephen McColm2, Louise-Marie Craigie1

  • 1School of Chemistry, The University of Edinburgh, Edinburgh EH9 3FJ, U.K.

ACS catalysis
|November 21, 2024
PubMed
概括

研究人员重新编程了多基酸合成酶 (PKS) 模块,从脂肪酸中产生有价值的2 - 甲基格尔贝特脂质. 这种工程酶系统为生产工业化学品提供了可持续的途径.

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