根据已确定的风险因素,建议针对Gardnerella vaginalis的查标准
Afrida Sara1, Apurva Ramanujam1, Dhiya Ram1
1Rheumatology, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, USA.
Cureus
|November 21, 2024
概括
像吸烟,SES和遗传学等鲜为人知的因素显著影响Gardnerella vaginalis (GV) 感染,导致细菌性阴道炎 (BV). 识别这些风险可以改善临床医生的查工具.
科学领域:
- 妇科 妇科 妇科 妇科
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 细菌性阴道炎 (BV) 与乳酸菌的降低调节和Gardnerella vaginalis (GV) 的上升调节有关.
- 确定的GV感染风险因素存在,但不太知名的因素需要进一步调查.
研究的目的:
- 进行范围审查,确定对Gardnerella vaginalis (GV) 感染的鲜为人知的风险因素.
- 根据已识别的风险因素,为临床医生提出一个更新的,基于点的查工具.
主要方法:
- 在Embase,Ovid MEDLINE和Web of Science数据库中进行系统搜索.
- 在选 438 个最初收集的文章后,包括了 31 篇文章.
主要成果:
- 与GV的积极关联包括性活动,透性阴道和口交,未受保护的性行为和特定的避孕方法.
- 较低的教育水平和更高的社会经济地位 (SES) 与增加的GV殖民化相关.
- 在GV和吸烟/尼古丁使用,特定种族 (撒哈拉以南非洲人口),遗传因素 (sialidase A基因) 和解剖因素 (短宫) 之间发现了显著的相关性.
- 阴道冲洗也与增加的GV感染有关.
结论:
- 较少知名的风险因素,如吸烟,种族,SES,遗传学和解剖学显著影响GV感染和BV.
- 采用这些因素的更新查工具可以帮助临床医生及时诊断和管理,特别是在高风险人群 (如孕妇和免疫受损者) 中.
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