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Updated: Jun 7, 2025

Induction of Protein Deletion Through In Utero Electroporation to Define Deficits in Neuronal Migration in Transgenic Models
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鉴定FBLL1作为一种神经元特异性RNA 2'-O-甲基转移酶介导神经元分化的神经元特异性RNA

Deyu Zhang1, Bo Li1, Henan Xu1

  • 1State Key Laboratory of Medicinal Chemical Biology, Institute of Immunology, College of Life Sciences, Nankai University, Tianjin 300071, China.

Proceedings of the National Academy of Sciences of the United States of America
|November 21, 2024
PubMed
概括

纤维拉林样蛋白1 (FBLL1) 是一种新型的2'-O-甲基转移酶,通过甲基化GAP43 mRNA来促进神经元分化. 这一发现促进了对神经生物学和疾病中的RNA修饰的理解.

关键词:
通过2′-O-甲基化.的RNA甲基转移酶.基因组RNA的修饰 基因组RNA的修饰纤维激素就像蛋白质1一样神经元分化的神经元差异化

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