从1985年到2022年,德国最常被处方的10种药物:药理学分析
Lennart Schröder1, Roland Seifert2
1Institute of Pharmacology, Hannover Medical School, D-30625, Hannover, Germany.
Naunyn-Schmiedeberg's archives of pharmacology
|November 21, 2024
概括
这项研究分析了德国38年顶级药物的处方数据,以了解处方趋势. 这些发现有助于预测未来的毒品使用情况,并防止全球的毒品短缺.
科学领域:
- 卫生经济学 卫生经济学
- 制药政策 制药政策
- 药物监督 药物监督 药物监督
背景情况:
- 药品支出是德国法定医疗保险基金 (SHI) 的一个主要成本.
- 由于药物在医疗保健中的重要作用,了解处方变化至关重要.
- 2022年前十大药物占每日处方剂量的41%以上.
研究的目的:
- 分析1985年至2022年德国前十大药物的处方趋势.
- 确定近四十年来药物处方模式变化背后的多方面的原因.
- 为预测未来的药物处方和防止潜在的短缺提供数据.
主要方法:
- 对前10种药物的处方定义每日剂量 (DDD) 和每DDD的成本进行分析.
- 数据来源于Arzneiverordnungsreport (AVR),涵盖1986年至2023年的时间.
- 在38年 (1985-2022) 的时间里,长度研究检查了药物处方行为.
主要成果:
- 确定了处方增加的关键驱动因素,包括通用药的引入,积极的研究,降价,扩展的适应症和指导方针的变化.
- 确定了处方减少的关键驱动因素,包括竞争对手的仿制药推出,竞争对手的积极研究,负面研究和安全性讨论.
- 观察到,改变处方的原因有时可能是不合理的.
结论:
- 这一全面的长期分析为德国药物处方动态提供了宝贵的见解.
- 这些发现对于预测未来的处方趋势和主动管理药物供应链至关重要.
- 这项研究的含义扩展到全球,有助于防止全球药物短缺.
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