对治疗肠-大脑相互作用障碍的非药理干预措施的经济评估:一个范围审查
Anton Pak1, Madeline O'Grady2, Gerald Holtmann3,4
1Centre for the Business and Economics of Health, The University of Queensland, Brisbane, QLD, 4072, Australia. a.pak@uq.edu.au.
PharmacoEconomics
|November 21, 2024
概括
对肠-大脑相互作用障碍的非药物治疗方法具有不同的成本效益. 认知行为疗法,饮食干预和神经神经调节是具有成本效益的,与针和物理治疗不同. 需要进一步的研究来提高证据的质量.
科学领域:
- 卫生经济学 卫生经济学
- 胃肠病学 胃肠病学
- 神经胃肠病学 神经胃肠病学
背景情况:
- 肠-大脑相互作用的障碍是普遍存在的,并且是负担.
- 药物治疗对这些疾病的有效性有限.
- 越来越多地使用非药物干预措施,但其成本效益尚不确定.
研究的目的:
- 进行首次审查,评估对肠-大脑相互作用障碍的非药物干预措施的经济评估证据.
- 评估这些治疗的价值对金钱的价值.
主要方法:
- 根据PRISMA-ScR指南进行了范围审查.
- 在多个数据库 (PubMed,Embase,Web of Science,Scopus,HTA数据库) 进行了搜索,这些数据库更新至2024年5月.
- 使用CHEQUE框架和CHEERS 2022的方法和报告质量进行了评估.
主要成果:
- 包括15项研究,主要涉及刺激性肠综合征治疗.
- 认知行为疗法,饮食干预和神经神经调节被发现是具有成本效益的.
- 针和物理治疗不具有成本效益,大多数研究都符合质量标准.
结论:
- 由于方法上的不一致性,证据库中存在关于稳定性和通用性的差距.
- 未来的研究应该集中在更长的后续行动,全面的成本评估和子组分析上.
- 建议在未来的研究中对建模假设和股权考虑提供更明确的理由.
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