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Updated: Jun 7, 2025

A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth
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A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth

Published on: December 22, 2020

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胰腺CAF衍生自毒素驱动自克林CTGF表达以调节原原始信号传递

Fanny Volat1, Ragini Medhi1, Lauren Z Maggs1,2,3

  • 1Cancer Research Horizons, Cambridge, United Kingdom.

Molecular cancer therapeutics
|November 21, 2024
PubMed
概括

与癌症相关的纤维细胞通过自毒素 (ATX) 信号驱动胰腺癌的生长. 抑制ATX可以减少CTGF等促进瘤的因素,为胰腺管腺癌提供了一种新的治疗策略.

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