菌效应器HaRxL106与转录因子BIM1相互作用,改变了植物生长,BR信号和对病原体的敏感性
Maria Florencia Bogino1,2,3, Juan Marcos Lapegna Senz1,2, Lucille Tihomirova Kourdova1,2
1CIQUIBIC-CONICET, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, 5000, Argentina.
The Plant journal : for cell and molecular biology
|November 21, 2024
概括
虫病原体Hyaloperonospora arabidopsidis (Hpa) 通过准BIM1转录因子来操纵Arabidopsis植物. 这种相互作用增强了病原体的易感性,改变了植物的生长,揭示了植物-病原体相互作用的新机制.
科学领域:
- 植物病理学 植物病理学
- 分子植物-微生物相互作用
- 卵菌生物生物学 卵菌生物生物学
背景情况:
- 甲 (Hyaloperonospora arabidopsidis,简称Hpa) 是一种虫类病原体,会导致Arabidopsis的菌.
- RxLR效应器是Hpa分泌的关键毒性因子,用于操纵宿主植物.
- 了解效应体与宿主相互作用对于发展抗病能力至关重要.
研究的目的:
- 描述Hpa RxLR效应器HaRxL106和阿拉比多普西斯转录因子BIM1.1.之间的相互作用.
- 阐明BIM1在植物对病原体敏感性的作用.
- 研究HaRxL106操纵宿主生理学的机制.
主要方法:
- 在体外和植物内部的相互作用测试中,HaRxL106和BIM1.1之间的相互作用测试.
- 在BIM1依赖和独立的场景中评估植物对病原体的敏感性.
- 分析了对布拉辛类固醇 (BR) 敏感基因的转录激活.
- 观察植物生长表型.
主要成果:
- HaRxL106直接与阿拉比多普西斯的转录因子BIM1.1.相互作用.
- 对于HaRxL106来说,BIM1是必不可少的,以增加宿主对病原体的敏感性.
- HaRxL106利用BIM1诱导BR响应基因表达并改变植物生长,模仿避阴综合征.
- BIM1被确定为Hpa操纵的新型易感性因素.
结论:
- 在Hpa效应器HaRxL106的目标和操纵的Arabidopsis转录因子BIM1.1.
- 这种操纵通过改变宿主基因表达和生长模式来增强病原体的毒性.
- BIM1代表了布拉西诺固醇信号与植物免疫之间的交叉沟通的新环节,被病原体利用.
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