尼泊尔西部Sunwal市的2型糖尿病患者中与药物相关的问题
Sushma Chapagain1, Nabin Pathak2,3, Kushal Subedi4
1Pharmaceutical Sciences Program, Faculty of Health Sciences, School of Health and Allied Sciences, Pokhara University, Pokhara, Kaski, Nepal.
PloS one
|November 21, 2024
概括
在尼泊尔,超过一半的2型糖尿病患者经历了与药物相关的问题 (DRPs),主要是由于治疗有效性问题和不坚持. 药剂师的家庭访问确定了这些DRP,有助于疾病管理.
科学领域:
- 药理学 药理学是指药理学的学科.
- 临床药房 临床药房
- 公共卫生 公共卫生
背景情况:
- 2型糖尿病经常与高血压和脂质失调等疾病并存,增加了与药物相关问题的风险.
- 虽然药剂师在管理DRP方面的角色在高收入国家已经确立,但它们在低收入和中等收入国家的影响需要进一步探索.
- 这项研究的重点是确定尼泊尔特定地区的2型糖尿病患者的DRP.
研究的目的:
- 在被诊断为2型糖尿病的患者中识别与药物相关的问题 (DRP).
- 探索这种患者群体中遇到的DRP的患病率和类型.
- 了解2型糖尿病管理中与DRP相关的因素.
主要方法:
- 一项基于社区的横截面研究在尼泊尔卢宾尼省的Sunwal市镇进行 (2021年4月至11月).
- 用分层随机抽样招募了182名18岁或以上的2型糖尿病患者,这些患者正在服用抗糖尿病药物.
- 通过使用欧洲药物护理网络 (PCNE) V8.02工具来识别DRP,进行了家庭访问以进行处方审查.
主要成果:
- 很大一部分患者 (53.3%,n=97) 经历了DRP.
- 比古安化物 (49.7%) 和硫氨酸 (24.6%) 是最常被处方的药物类别,其中甲胺 (49.4%) 是DRP中最常涉及的药物.
- 治疗有效性问题 (79.61%) 和患者不坚持 (71.85%) 是主要的DRP,与糖尿病持续时间和水果摄入量有显著的关联.
结论:
- 大多数2型糖尿病患者研究了经验丰富的DRP,突出了疾病管理的重大挑战.
- 药剂师主导的家庭访问在识别DRP和相关因素方面被证明是有效的.
- 这些发现可以为DRP预防和改善类似环境中的2型糖尿病管理策略提供信息.
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