增加儿童接种疫苗的ADaptivE PrenaTal (ADEPT) 干预措施:集群随机试验和嵌套混合方法评估协议
Lavanya Vasudevan1,2, Rachael M Porter1, Ilse Campos1
1Hubert Department of Global Health, Emory University, Atlanta, Georgia, United States of America.
PloS one
|November 21, 2024
概括
这项研究评估了适应性产前干预,以减少父母对疫苗的犹,并增加儿童免疫. 研究结果将为主动的家长疫苗教育和及时的婴儿疫苗接种策略提供信息.
科学领域:
- 公共卫生 公共卫生
- 孕产妇和儿童的健康
- 疫苗学 疫苗学 疫苗学
背景情况:
- 有限的证据存在于产前干预措施,以减轻家长的疫苗犹.
- 本研究方案评估了适应性产前干预 (ADEPT) 对第一次怀孕的个人.
- 该干预措施旨在增加出生后儿童接种疫苗.
研究的目的:
- 评估ADEPT干预措施在增加儿童疫苗接种方面的有效性.
- 评估ADEPT干预后家长对疫苗犹的变化.
- 确定产前干预措施对婴儿及时免疫接种的影响.
主要方法:
- 一个集群随机试验与嵌套的解释混合方法设计.
- 干预组与标准护理一起接受ADEPT;对照组仅接受标准护理.
- 主要结果:2个月的儿童及时接种疫苗;次要结果:减少对疫苗的犹.
主要成果:
- 数据收集正在进行中;有效性和对疫苗犹的影响尚未确定.
- 儿童疫苗接种结果将从免疫登记册中提取出来.
- 父母接种疫苗的意图将在干预前和后进行评估.
结论:
- 预计研究结果将提供关于产前干预疗效的证据.
- 这项研究旨在主动解决父母对疫苗的犹.
- 这项工作旨在促进及时的儿童疫苗接种.
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